GMP-compliant manufacturing process for syrup-form dietary supplements.

The syrup dosage form is one of the most common dosage forms in dietary supplement manufacturing plants. With many outstanding advantages, syrup is the most widely used type. Especially products for children and the elderly.

What is dietary supplement syrup?

The syrup product of a dietary supplement manufacturing plant is a liquid form of drink, produced from a liquid mixture consisting of functional ingredients, vitamins, sugar, mineral water, and plant extracts.

Syrup usually has a sweet taste, and coloring agents, thickeners, antioxidants, and additives may be added to improve the quality and features of the product.

Dietary supplement syrup products are often designed to provide nutrients, support health, and help supplement nutrients deficient in the body. They can be used to boost the immune system, supplement vitamins, minerals, ... and many other benefits.

Syrup products are usually packaged in bottles or jars with tight-fitting lids for storage and convenience. This product can be consumed directly or diluted with water or other liquids before drinking.

In summary: Syrup is a liquid, viscous solution. Because syrup contains a large amount of sugar, it is prepared by dissolving active ingredients and medicinal substances in simple syrup or by dissolving sugar in a solution of medicinal substances and flavorings.

Advantages of syrup dosage forms

Has a stable solution structure.

Simple preparation method.

Homogeneous drug solution, so it is easy to divide the standard dose.

The solution form has a rapid effect when used, with high bioavailability.

Suitable for use by children and the elderly. Because it is easier to use than tablets and capsules. The taste of syrup is sweet, fragrant, and easy to drink.

Process of manufacturing dietary supplements in syrup form

How is the production process of dietary supplements?

Production process

• Step 1: Receive raw materials into the warehouse.
• Step 2: Take samples for testing raw materials.
• Step 3: Transfer the tested raw materials to the production workshop.
• Step 4: Prepare the base solutions, mix homogeneously.
• Step 5: Bottle filling.
• Step 6: Packaging into finished product boxes.
• Step 7: Take samples of bottled and boxed finished products for testing.
• Step 8: Warehousing / Record keeping / Sample retention and Distribution.

All steps in the above production process must be strictly controlled according to strict standards and use cleanroom equipment to meet the high requirements of the production environment.

After the steps of production on the line, the finished product will continue to be sampled for testing according to regulations. The requirement of this step is that 100% of the batch meets the quality standards for distribution to the market.

Notes in the processes

In steps 1 and 2:

When receiving raw materials into the warehouse: check the CA, CO and other criteria as announced for the raw material being tested, such as microbiological and heavy metal criteria.

Check the quantity and origin of the raw material batch.

Based on the production schedule, the issued formula of the product, the warehouse keeper issues the correct raw materials according to the order slip.

Check that the raw materials ensure the required taste, color, and state.

In steps 3, 4, 5, 6

Carrying out the homogenization process and manufacturing dietary supplements requires an automatic line with a system of modern machinery and equipment, including:

• Liquid packaging machine.
• Automatic liquid tube filling machine line.
• Syrup filling machine line.
• Stainless steel tank for containing and cooling syrup.
• Intermediate stainless steel syrup tank.
• Roll labeler.
• Heat sealing machine with date printing.
• Inkjet printer.
• Tube labeling machine.

Conditions for manufacturing GMP-compliant dietary supplement syrup

The production area must ensure disinfection conditions according to current hygiene regulations.

Mixing room equipment and tools must be cleaned and disinfected before each production shift with food-grade alcohol. Run the dehumidifier so that after mixing, the moisture content of the product is below 10% and the room temperature is below 20 degrees Celsius.

Accurately quantify raw materials according to the issued formula.

Retained samples: After each step, samples must be taken for control testing. After the quality control results are standard-compliant, the QA department allows the transfer to the packaging stage.

All steps in the syrup production process are controlled according to strict standards.

Reputable unit consulting on building a GMP-compliant dietary supplement manufacturing plant

With a team of experienced professionals, we support customers in choosing optimal and scientific technology and production processes, in accordance with GMP standards.

We - Anh Khang M&E always have comprehensive solutions from the planning and consulting stage, cleanroom design and construction, and equipment consulting. This helps provide customers with synchronized and accurate products in a short time.

For more information on the production process of pharmaceuticals, dietary supplements, cosmetics, ... please contact the hotline for the fastest support.

For detailed information on CLEANROOM CONSULTATION - DESIGN - CONSTRUCTION, please contact:

Anh Khang Cleanroom Mechanical Electrical Joint Stock Company Hotline: 1900 636 814 Email: info@akme.com.vn Website: akme.com.vn Add: Lot B7 Xuan Phuong Garden, Trinh Van Bo Street, Phuong Canh Ward, Nam Tu Liem District, Hanoi.